| Sat, Aug 9 2025 12:00 PM |
2 |
New York Giants |
Buffalo Bills |
- |
Highmark Stadium |
NFL Net |
| Sun, Aug 17 2025 7:00 PM |
3 |
Buffalo Bills |
Chicago Bears |
- |
Soldier Field |
FOX |
| Sat, Aug 23 2025 6:30 PM |
4 |
Buffalo Bills |
Tampa Bay Buccaneers |
- |
Raymond James Stadium |
ESPN Unlmtd, WFLA-TV |
| Sun, Sep 7 2025 7:20 PM |
1 |
Baltimore Ravens |
Buffalo Bills |
40 - 41 |
Highmark Stadium |
NBC |
| Sun, Sep 14 2025 12:00 PM |
2 |
Buffalo Bills |
New York Jets |
30 - 10 |
MetLife Stadium |
CBS |
| Thu, Sep 18 2025 7:15 PM |
3 |
Miami Dolphins |
Buffalo Bills |
21 - 31 |
Highmark Stadium |
Prime Video |
| Sun, Sep 28 2025 12:00 PM |
4 |
New Orleans Saints |
Buffalo Bills |
19 - 31 |
Highmark Stadium |
CBS |
| Sun, Oct 5 2025 7:20 PM |
5 |
New England Patriots |
Buffalo Bills |
23 - 20 |
Highmark Stadium |
NBC |
| Mon, Oct 13 2025 6:15 PM |
6 |
Buffalo Bills |
Atlanta Falcons |
- |
Mercedes-Benz Stadium |
ESPN |
| Sun, Oct 26 2025 12:00 PM |
8 |
Buffalo Bills |
Carolina Panthers |
- |
Bank of America Stadium |
FOX |
| Sun, Nov 2 2025 3:25 PM |
9 |
Kansas City Chiefs |
Buffalo Bills |
- |
Highmark Stadium |
CBS |
| Sun, Nov 9 2025 12:00 PM |
10 |
Buffalo Bills |
Miami Dolphins |
- |
Hard Rock Stadium |
CBS |
| Sun, Nov 16 2025 12:00 PM |
11 |
Tampa Bay Buccaneers |
Buffalo Bills |
- |
Highmark Stadium |
CBS |
| Thu, Nov 20 2025 7:15 PM |
12 |
Buffalo Bills |
Houston Texans |
- |
NRG Stadium |
Prime Video |
| Sun, Nov 30 2025 3:25 PM |
13 |
Buffalo Bills |
Pittsburgh Steelers |
- |
Acrisure Stadium |
CBS |
| Sun, Dec 7 2025 3:25 PM |
14 |
Cincinnati Bengals |
Buffalo Bills |
- |
Highmark Stadium |
FOX |
| Sun, Dec 14 2025 12:00 PM |
15 |
Buffalo Bills |
New England Patriots |
- |
Gillette Stadium |
CBS |
| Sun, Dec 21 2025 12:00 PM |
16 |
Buffalo Bills |
Cleveland Browns |
- |
Huntington Bank Field |
CBS |
| Sun, Dec 28 2025 3:25 PM |
17 |
Philadelphia Eagles |
Buffalo Bills |
- |
Highmark Stadium |
FOX |
| Sat, Jan 3 2026 11:00 PM |
18 |
New York Jets |
Buffalo Bills |
- |
Highmark Stadium |
|
